When a patient enters the emergency department presenting with the symptoms of a myocardial infarction (MI), every moment is critical. Achieving favorable clinical and operational outcomes requires fast and accurate chest pain assessment at the point of care, as well as coordination with the laboratory for quality assurance. Having high-sensitivity troponin testing at the point of care—producing accurate results in just 8 minutes—could transform care delivery for millions of people each year, improving ED throughput, reducing stress and strain on acute care clinicians, and aiding in optimizing the use of time and resources of busy laboratories.